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          6                                                                                 HEALTH AND LABORATORY MAGAZINE




          A BLOOD TEST MAY HELP                                                              2020 TOKYO


          PREDICT RECOVERY FROM                                                                  OLYMPIC


          TRAUMATIC BRAIN INJURY                                                                   GAMES













          High levels of a key
          blood protein point to
          brain shrinkage and

          damage to message -
          sending axons






          Elevated blood levels of a   Graham of Imperial College    “No two traumatic brain in-
          specific protein may help   London and his colleagues   juries are alike,” says David   Olympic games ended after one
          scientists predict who has   found.               Okonkwo, director of the   year delay and without audience.
          a better chance of bounc-                         Neurotrauma Clinical Trials
          ing back from a traumatic   These researchers also   Center at the University of
          brain injury.            had a unique opportunity   Pittsburgh. Scientists have   We are still going   with 13 medals, two gold
                                   to check that the blood   been looking for biomark-  through a pandemic    and two silver as well as
          The protein, called neu-  biomarker, which gives in-  ers of TBI injury such as NfL   measures since 2019,   9 bronze. The medals
          rofilament light or NfL   direct clues about the brain   to develop injury-specific   and we had to postpone   that Turkey won in the
          for short, lends structural   injury, actually measured   interventions, and Okonk-  everything, including the   2020 Olympic Games
          support to axons, the ten-  what was happening in the   wo says these new findings   most important things,   were as follows;
          drils that send messages   brain. In 18 of the partici-  are promising for patients   during this duration. The
          between brain cells. Levels   pants that needed brain   whose injury has damaged   2020 Tokyo Olympics   Mete Gazoz, Archery,
          of NfL peak on average at   surgery, researchers sam-  their axons.          was another organi-    Gold Medal
          10 times the typical level   pled the fluid surrounding                      zation affected by this   Busenaz Sürmeneli, Box,
          20 days after injury and   injured neurons. NfL con-  “We have not had the tools   situation. Although the   Gold Medal
          stay above normal a year   centrations there correlat-  to measure a specific injury   Olympic Games took   Eray Şamdan, Karate,
          later, researchers report   ed with NfL concentrations   type of an individual pa-  a shorter time than the   Silver Medal
          September 29 in Science   in the blood.           tient,” Okonkwo says. While   pandemic, they gave   Buse Naz Çakıroğlu,
          Translational Medicine. The                       this test probably is still a   us a taste of excite-  Box, Silver Medal
          higher the peak NfL blood   “The work shows that a                           ment, fighting spirit and   Hakan Reçber, Taek-
          concentrations after injury,   new ultrasensitive blood   few years from use in U.S.   sportsmanship as well   wondo, Bronze Medal
          the tougher the recovery                          clinics, other large research   as improved our morale.  Hatice Kübra İlgün,
          for people with traumatic   test can be used to accu-  groups are looking for                       Taekwondo, Bronze
          brain injury (TBI) six and 12   rately diagnose traumatic   ways to use NfL and other   Let’s look at the over-  Medal
          months later, shows the   brain injury,” says Graham.   blood-based biomarkers   all standings at the   Rıza Kayaalp, Wrestle,
          study of 197 people treat-  “This blood test can predict   for diagnosing TBI and   Olympic Games: The   Bronze Medal
          ed at eight trauma centers   quite precisely who’s going   creating opportunities for   USA took the first place   Yasemin Adar, Wrestle,
          across Europe for moder-  to make a good recovery   intervention.            with 39 gold, 41 silver   Bronze Medal
          ate to severe TBI.       and who’s going to have                             and 33 bronze medals,   Ferhat Arıcan, Gymnas-
                                   more difficulties.”      ________________________   overtaking China, which   tics, Bronze Medal
          Brain scans of 146 partic-                        onal marker neurofilament   was long behind. China   Taha Akgül, Wrestle,
          ipants revealed that their   Study participants were   light predicts long-term   was second with 38   Bronze Medal
          peak NfL concentrations   adults and mostly male,   outcomes and progressive   gold, 32 silver and 18   Ali Sofuoğlu, Karate,
          predicted the extent of   so more work needs to be   neurodegeneration after   bronze medals. Japan   Bronze Medal
          brain shrinkage after six   done to determine if these   traumatic brain injury  finished third with 27   Merve Çoban, Karate,
          months, and axon dam-    findings apply to women,                            gold, 14 silver and 17   Bronze Medal
          age at six and 12 months   children and people with   Research Article|Science   bronze. Turkey finished   Uğur Aktaş, Karate,
          after injury, neurologist Neil   mild TBI.        Translational Medicine|    the games in 35th place   Bronze Medal
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