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THE OLDEST BLACK

HOLE EVER FOUND

LC-MS/MS Analysis of

Steroid Hormones in Serum

Steroid hormones are characterized as effective biological messengers which take part in body regulation processes such as development,
reproduction, stress, and growth even at low concentrations. Thus, reliable and simultaneous analysis of a broad panel of steroid hormones
plays vital role for the investigation of the hormone profile, which could be useful in detection endocrine disorders resulting from defects in
steroid biosynthesis such as congenital adrenal hyperplasia (CAH). Due to the restrictions and shortcomings of immunoassay techniques for
measurement of steroid hormones in body fluids, liquid chromatography tandem mass spectrometry (LC-MS/MS) is increasingly becoming
the method for multi-class steroid hormone detection and quantification.
Jasem’s approach is offering simultaneously quantification of clinically foremost 16 steroid hormones by LC-MS/MS in 16 minutes.

Features of Jasem-Steroid Hormone LC-MS/MS Analysis Kit Parameters
• No derivatization required • 17-α-Hydroxyprogesterone
• One sample preparation for all steroid hormones-Simple liquid/liquid extraction • Aldosterone
(LLE) protocol • Testosterone
• Measurement of multi-class steroids in a single run without sacrificing analysis time • Estradiol
• Ensure accurate quantitation, high sensitivity and selectivity comparing to • Progesterone
immunoassays • Cortisol
• Dihydrotestosterone
• Androstene-3,17-dione
• Corticosterone
• 11-Deoxycortisol
• Pregnenolone
• 11-Deoxycorticosterone
• DHEA
• DHEAS
• 17-α-Hydroxypregnenolone
• Androsterone

Jasem Laboratuvar Sistem ve Çözümleri San. ve Tic. A.Ş. www.jasem.com.tr
Barbaros Mah. Temmuz Sk. No:6 Sem Plaza Ataşehir, İstanbul
T: +90 216 571 02 00 F: +90 216 571 02 02