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volunteers performed a
variety of activities in the
lab, from sitting and stand-
ing, to jogging, biking, and
lifting weights.

From the stickers’ imag- IN BIOEXPO
es, the team was able to
observe the changing di- Powerful events
ameter of major blood ves-
sels when seated versus
standing. The stickers also Cutting-edge technologies
captured details of deeper
organs, such as how the Inovative developments
heart changes shape as it
exerts during exercise. The
researchers were also able
to watch the stomach dis-
tend, then shrink back as
volunteers drank then later
passed juice out of their
system. And as some vol-
unteers lifted weights, the
team could detect bright
patterns in underlying mus-
cles, signaling temporary
microdamage.
“With imaging, we might
be able to capture the mo-
ment in a workout before
overuse, and stop before
muscles become sore,”
says Chen. “We do not
know when that moment
might be yet, but now we
can provide imaging data
that experts can interpret.”

The team is working to
make the stickers function
wirelessly. They are also
developing software algo-
rithms based on artificial
intelligence that can better
interpret and diagnose
the stickers’ images. Then,
Zhao envisions ultrasound
stickers could be packaged
and purchased by patients
and consumers, and used
not only to monitor various
internal organs, but also
the progression of tumors,
as well as the development
of fetuses in the womb.

“We imagine we could have
a box of stickers, each
designed to image a differ-
ent location of the body,”
Zhao says. “We believe this
represents a breakthrough
in wearable devices and
medical imaging.”
Bioadhesive ultrasound
for long-term continuous
imaging of diverse organs

https://www.science.
org/doi/10.1126/science.
abo2542